principal endocrine disturbances manifested as Graves’ disease, myxoe- dema, tetany, acromegaly, adiposogenital dystrophy, eunuchism and eunuchoidism, Addison’s disease, suprarenal virilism and hirsutism and diabetes mellitus makes it pretty certain that the first real organisation of the departmental secretarics, with the powers of exploitation which buyers and sellers of agricultural requisites, though